Author: Katie Wilson
In the News
Following Record-Breaking Fundraising Year, Pelotonia 2026 Registration Opens on March 4 with New Experiences
| February 17, 2026
PELOTONIA INTRODUCES NEW 17-MILE RIDE WEEKEND ROUTE AND MOUNTAIN BIKING AT GRAVEL DAY
COLUMBUS, Ohio (February 17, 2026) – Pelotonia will launch registration for 2026 participants on Wednesday, March 4, at 12 p.m. ET. This year’s Pelotonia events will include Opening Ceremony on July 31, Ride Weekend on August 1 and 2 and Gravel Day on October 3. Participants can register as Riders, Runners/Hikers, Volunteers or Challengers at pelotonia.org/register.
New in 2026, Pelotonia has added a 17-mile loop route to Ride Weekend, its shortest road cycling distance to date, designed to welcome new Riders and expand accessibility across all experience levels. The new route will start and finish at North Bank Park in downtown Columbus on Saturday morning, taking Riders through Bexley and The Ohio State University campus. Plus, mountain biking routes are new for Gravel Day 2026, the fourth year of the event with outdoor adventures on the gravel roads and scenic trails of southeast Ohio.
“Pelotonia is powered by tens of thousands of people who believe there are no limits to our impact,” said Joe Apgar, CEO of Pelotonia and cancer survivor. “As we kick off 2026, we’re energized by the momentum of a record-breaking year and grateful to every participant, donor and partner who fuels our mission. Because this community continues to show up year after year, researchers at the OSUCCC – James are advancing breakthroughs in cancer research that are saving lives. Whether it’s your first year or your 18th Ride Weekend, we invite you to join us and help keep the momentum going.”
Since 2009, Pelotonia participants have raised more than $339 million, directing 100 percent of every dollar to accelerate innovative cancer research at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) thanks to the support from generous funding partners. In 2025, the Pelotonia community raised $29.2 million. The milestone marked the largest single-year fundraising total in Pelotonia history, and the organization is looking to make an even bigger impact in 2026.
“Pelotonia fuels science that transforms what we can offer patients,” said W. Kimryn Rathmell, MD, PhD, CEO of the James Cancer Hospital and Solove Research Institute and Director of The Ohio State University Comprehensive Cancer Center. “Because this community invests so boldly in discovery, our teams explore new ideas, develop new treatments, and bring world-class talent to Ohio State. As we begin this new year, I am deeply grateful to every participant whose commitment pushes research forward and expands what’s possible for patients, families and communities.”
2026 Theme: No Limits
Each Pelotonia annual campaign kicks off with a new creative theme, arrow design and messaging to support recruitment and fundraising efforts. The Pelotonia 2026 theme is No Limits, celebrating the unstoppable determination of the Pelotonia community and the boundless potential of innovative cancer research. The theme reflects the bold spirit of a community that refuses to accept limits on the journey to Ending Cancer. The 2026 creative campaign and arrow design embody vibrancy, high energy, forward momentum and collective power to do good. Watch the 2026 Launch Video here.
Opening Ceremony on July 31 and Ride Weekend on August 1-2
Opening Ceremony is a community-rallying party of 15,000-20,000 guests in downtown Columbus to kick off Ride Weekend. On July 31, attendees will enjoy the celebration featuring an inspirational stage program and live music entertainment. The 2026 Opening Ceremony headliner act will be announced this spring. Last year’s headliner was platinum-selling rock band O.A.R.
Now in its 18th year, Ride Weekend gathers more than 7,500 Riders, 3,000 Volunteers and countless spectators on August 1-2. Road cycling route distances range from 17 to 165 miles with fundraising commitments starting at $1,250. Ride routes and start/finish lines will offer incredible new experiences alongside community favorites, with several routes to choose from, welcoming participants from varied skill levels and experiences to be part of the Pelotonia community’s signature weekend. One-day ride options range from 17 to 100-mile routes. Those interested in the two-day rides of 131 or 165 miles will have the option of an overnight stay at Kenyon College. Route overviews are listed below.
Saturday, August 1:
- NEW 17-Mile Route: Downtown Columbus Loop through Bexley and Ohio State campus
- 23-Mile Route: Downtown Columbus to New Albany Schools
- 46-Mile Route: Downtown Columbus to Abercrombie & Fitch Co. Headquarters in New Albany
- 66-Mile Route: New Albany Schools to Kenyon College in Gambier
- 100-Mile Route: Downtown Columbus to Kenyon College in Gambier
Sunday, August 2:
- 27-Mile Route: New Albany Loop
Two-Day Routes:
- 131-Mile Route (Saturday 66-Mile Route and Sunday 65-Mile Route): New Albany Schools to Kenyon College in Gambier on Saturday; Gambier to New Albany Schools on Sunday
- 165-Mile Route (Saturday 100-Mile Route and Sunday 65-Mile Route): Downtown Columbus to Kenyon College in Gambier on Saturday; Gambier to New Albany Schools on Sunday
- Any Saturday Route and 27-Mile Loop on Sunday
Gravel Day on October 3
Gravel Day offers unique adventures on the scenic, gravel roads and outdoor trails of southeast Ohio. Hosted at Snow Fork Event Center in Nelsonville, Ohio, participants can ride, run or hike, with a minimum fundraising commitment of $1,500.
Gravel Riders can select from 11, 25 and 48-mile looped gravel cycling route options through the hills of Athens County. Two new mountain biking routes join Gravel Day, including 10 and 24-mile options, where Riders will experience the Baileys Trail System of world-class machine-built mountain biking trails including a mix of IMBA-rated green (“easy”) and blue (“more difficult”) trails.
The Trail Run/Hike, introduced in 2025 and exceeded expectations with more than 350 Runners and Hikers in its first year, is a 3.5-mile looped course through the picturesque property of Snow Fork Event Center, with flexible start times and optional additional laps. Participants may opt to challenge themselves to both ride and run/hike at Gravel Day. For this option, Riders will first complete their selected cycling route — gravel ride or mountain biking — then enter the Trail Run/Hike course.
Saturday, October 3:
- 11-Mile Gravel Route: Loop with more than 900 feet total elevation gain
- 25-Mile Gravel Route: Loop with more than 1,600 feet total elevation gain
- 48-Mile Gravel Route: Loop with more than 4,200 feet total elevation gain
- NEW 10-Mile Mountain Biking: Course with more than 1,000 feet total elevation gain
- NEW 24-Mile Mountain Biking: Course with more than 2,500 feet total elevation gain
- 3.5-Mile Trail Run/Hike: Loop course with option to complete as many times as desired during the course open hours of 10 a.m. to 2:30 p.m.
To extend the Gravel Day weekend experience, a Friday night community gathering at Snow Fork Event Center includes live music, food, drinks and s’mores. Overnight camping is also available for participants and supporters in tents, RVs and cars, which has grown in popularity the past two years.
Volunteers
More than 3,000 Volunteers support Ride Weekend and Gravel Day. Roles include bike management, first aid, food and beverage, merchandise sales and more. To learn more about Volunteer opportunities, a full list of role descriptions and opportunities is available on the Pelotonia website.
Launch Week Open Houses on March 4-5
The public is invited to Launch Week 2026 Open Houses at Pelotonia headquarters, located within The Ohio State University’s innovation district on west campus at the Energy Advancement and Innovation Center (2281 Kenny Road, Suite 450) and next door to the Pelotonia Research Center, which was named in recognition of Pelotonia’s partnership and philanthropic support for accelerating cancer research at Ohio State.
Launch Week 2026 Open Houses:
- Wednesday, March 4: 4 p.m. to 6 p.m.
- Thursday, March 5: 8:30 a.m. to 10 a.m.
Open to all participants and new supporters interested in ways to get involved, the events will kick off the year with connection and excitement. Attendees will enjoy food and drinks, meet Pelotonia-funded Scholars to learn about their cancer research, and participate in games to win prizes. Pelotonia merchandise, including a new Homage collection with custom designs and various branded apparel for adults and youth, will be available to purchase onsite. Attendees may also pick up 2026 Pelotonia arrow car magnets and yard signs, which are free to the community to display their support.
2025 Impact Report Now Available
In collaboration with the OSUCCC – James, Pelotonia released its 2025 Impact Report highlighting the events and initiatives that fuel innovative cancer research. The annual report provides the community with updates from the OSUCCC – James on Pelotonia-funded research and investments made with the support of Pelotonia dollars.
Research highlights within the 2025 Impact Report include:
- The first-of-its-kind, nationwide decentralized clinical trial conducted entirely by telehealth launched with support from a Pelotonia Idea Grant, led by Sameek Roychowdhury, MD, PhD, who was named the 2025 Pelotonia-Funded Researcher of the Year.
- 7 new Pelotonia Idea Grants worth $1.8 million were awarded to support cutting-edge, early-stage research. Additional Idea Grant spotlights in this report include research on contributions to non-small cell lung cancer and possible new treatments for this deadly disease and a paradigm-shifting study on why the body’s immune system T cells can fail, launching a new approach to immunotherapy treatment.
- An update on progress of the first drug fully developed at Ohio State for treating patients with solid tumors or non-Hodgkin lymphoma shares that it is expanding and will soon also be offered in a clinical trial for acute myeloid leukemia (AML).
- A new first-in-human clinical trial for glioblastoma offers hope for patients with this aggressive form of brain cancer in a study led by investigators at the Pelotonia Institute for Immuno-oncology (PIIO).
- Ohio State has recruited more than 300 top cancer scientists with Pelotonia support. Four individual spotlights feature a few of these talented new recruits — plus Glen Barber, PhD, FRS, who was recruited in 2024 and named to Citation Laureate for Nobel-class research.
- More than $2.5 million for 22 scholarships were awarded for Pelotonia Scholars including research impacting chronic lymphocytic leukemia (CLL), cancer genetics, urothelial carcinoma, the most common type of bladder cancer and more. 734 Pelotonia Scholars from 53 countries and 36 U.S. states have been funded since 2010.
- Charts within the report show the breakdown by category of research investments at the OSUCCC – James from the funding of Pelotonia in 2024 and since inception.
To learn more about the impact of Pelotonia dollars, visit pelotonia.org/impact.
Anyone interested in participating in Pelotonia 2026 can register on March 4 at noon ET at pelotonia.org/register.
No Limits: Pelotonia 2026
2026 Launch Video
Watch and share the Pelotonia 2026 Launch Video to experience the energy behind No Limits and get excited for what’s new in Pelotonia 2026, including new Ride Weekend routes, mountain biking added to Gravel Day, and more Pelotonia Kids events for our youngest Riders!
In the News
NO LIMITS: Pelotonia 2026 Theme Revealed
| February 16, 2026
The Pelotonia 2026 theme is: No Limits
Each Pelotonia year kicks off with a new creative theme, arrow design, and messaging to support your fundraising efforts and rally together as a community of Riders, Runners, Hikers, Volunteers, and Challengers committed to accelerating innovative cancer research at the OSUCCC – James.
In 2026, the Pelotonia community’s impact has No Limits.
“No Limits” captures the spirit of Pelotonia in this moment. To continue our momentum more vibrantly than ever.
It’s urgent. It’s optimistic. It’s electric.
It’s a call to move boldly, think bigger, and fuel breakthroughs without boundaries.
Progress is accelerating. Innovative cancer research is advancing faster than ever — but only if we continue fueling it.
This theme reflects the pace and purpose of Pelotonia. You continue to push beyond what’s possible. Refusing to slow down in the pursuit of our mission. We just had our biggest fundraising year ever. But momentum only matters if we keep moving.
The Pelotonia community won’t stop until we cross the only finish line that truly matters: Ending Cancer.
Fueling Research Breakthroughs without Boundaries
At Night of Impact last November, as we celebrated a record-breaking fundraising total in 2025, Dr. Sameek Roychowdhury, who was awarded Pelotonia-Funded Researcher of the Year, reflected on the extraordinary momentum of this community — and the pace of innovation happening in cancer care because of investments in research. He shared how Pelotonia funding is advancing groundbreaking work, including his nationwide telehealth clinical trial — the first of its kind — expanding access to precision cancer care through the OSUCCC – James to every zip code across the U.S.
It was in that context, as Dr. Roychowdhury talked about your impact and the bold innovation your Pelotonia dollars are funding, that he used the phrase “No Limits,” resonating with us that evening, and now energizing our community as the 2026 theme main message as we kick off another fundraising campaign to invest in the future of cancer research and researchers at the OSUCCC – James.
2026 Arrow, Car Magnets, and Yard Signs
The Pelotonia 2026 arrow design is a glowing, vibrant symbol of ongoing forward progress and community momentum. With 18 lines to celebrate our 18th year, the 2026 arrow is featured in the new car magnets and yard signs for the community to outwardly share their Pelotonia support this year.
Visit Pelotonia HQ for 2026 Launch Week Open Houses on March 4 from 4-6pm or March 5 from 8:30-10am to pick up your new car magnets, yard signs, and stickers featuring this year’s theme.
Join Us for Pelotonia 2026!
Join us and make an impact on innovative cancer research at the OSUCCC – James through your Pelotonia participation!
- Ride Weekend: August 1–2, 2026
- Gravel Day: October 3, 2026
- Registration opens on Wednesday, March 4, at noon EST!
Thanks to our generous funding partners, 100% of every participant-raised dollar goes directly to innovative cancer research at the OSUCCC – James.
Community Pride
No Limits: Pelotonia 2026
No Limits: Pelotonia 2026
2026 Launch Video
Watch and share the Pelotonia 2026 Launch Video to experience the energy behind No Limits and get excited for what’s new in Pelotonia 2026, including new Ride Weekend routes, mountain biking added to Gravel Day, and more Pelotonia Kids events for our youngest Riders!
Research Stories
New OSUCCC – James CEO Commends Community’s Devotion to Research
| September 19, 2025
W. Kimryn Rathmell, MD, PhD, the new CEO of Ohio State’s Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute (OSUCCC – James) marked her inaugural Pelotonia Ride Weekend with both a personal milestone and a vivid introduction to the vibrant, purpose-driven community fueling cancer research.
At Opening Ceremony, she stood before tens of thousands, immersing herself in the energy that defines Pelotonia, and then joined the more than 2,700 participants riding the 24-mile route on Saturday. Her experience underscored the profound partnership between the community and the groundbreaking cancer research led by the OSUCCC – James.
Dr. Rathmell spoke passionately about how critical Pelotonia’s support is for translating innovative science into real-world impact.
She emphasizes, “I can’t overstate how important the impact of Pelotonia’s support is on our cancer research. We do more innovative, more exciting and more powerful research because the community is behind us.”
These words reflect a core truth: while cutting-edge science is foundational to progress, it is the unwavering engagement, generosity and spirit of the Pelotonia community that helps fuel and accelerate breakthroughs at the OSUCCC – James.
Having previously served as director of the National Cancer Institute, she found Ohio State distinctly and deeply aligned with her passion — a synergy of discovery, compassionate patient care and community connection. She highlighted how the OSUCCC – James is uniquely poised to lead cancer research, treatment and prevention, thanks to the combined talents of researchers, clinicians and an engaged community that rallies together around a common purpose.
Dr. Rathmell described Pelotonia not simply as a fundraiser but as a movement with global reach. The people who join the ride — cancer survivors, families, scientists, caregivers, donors and volunteers — form a dynamic network whose shared commitment elevates the OSUCCC – James’ mission. This collective engagement shapes the research agenda itself, ensuring that it addresses real-world needs and fosters hope for all impacted by cancer.
Dr. Rathmell rode alongside participants during Ride Weekend, experiencing first-hand what it means to connect with the people and the mission driving Pelotonia.
Reflecting after finishing her first ride, she says, “I am energized. This is a tremendous experience.” Her participation exemplified the unity and purpose that fuel the community.
“Choosing to ride in Pelotonia helps to see the power that there is in coming together around something as important as cancer.”
This shared journey between researchers, clinicians, patients and supporters is what propels the science and care forward.
Beyond the event itself, Dr. Rathmell’s leadership vision hinges on deepening the connection between science and community. She believes that innovation thrives when informed by the stories and needs of those who face cancer. This approach not only shapes research priorities but also builds trust and hope in the broader community. Her goal is clear: to ensure research discoveries translate into accessible, effective care that improves outcomes for all.
In her role, Dr. Rathmell also carries the responsibility of mentoring and building the next generation of cancer scientists and clinicians. She has spoken about the importance of guidance in navigating the complexities of medical and scientific careers and the value of nurturing diverse talent committed to the mission of reducing cancer’s toll.
Her excitement about Ohio State’s cancer program is grounded in both its cutting-edge capabilities and its location at the cultural crossroads of rural, urban and diverse populations in Ohio. The OSUCCC – James is positioned to address disparities in cancer outcomes and develop prevention, detection and treatment that benefit broad communities.
Dr. Rathmell envisions a future where cancer prevention is widespread, early detection is accessible and new treatments mitigate suffering. “Ultimately, it will be a world where people don’t fear cancer the way we do today,” she says.
Dr. Rathmell’s first Ride Weekend embodied this spirit — standing shoulder to shoulder with riders and supporters, embracing the community and stepping into a leadership approach that blends scientific expertise with heartfelt commitment. Her arrival marks a new chapter for OSUCCC – James, one driven by innovation, collaboration and the unstoppable force of a community united in ending cancer.
Community Stories
Kids Bike Donations Honor High Rollers’ Commitment
| September 19, 2025
For years, Pelotonia’s High Rollers have exemplified generosity, passion, and a steadfast commitment to our mission. Traditionally, Pelotonia has marked their remarkable achievements with a special swag item as part of their annual Rider gift. Recently, however, thoughtful feedback was provided from the High Roller community: while these items were appreciated, they weren’t always necessary. In the spirit of listening to feedback and continually evolving our experience for the better, Pelotonia set out to reimagine the High Roller gift in a way that would powerfully reflect the values our High Rollers stand for.
In honor of the 2024 High Rollers, Pelotonia chose to make a meaningful, community-driven impact rather than distribute physical gifts. Instead of a swag item, Pelotonia donated brand-new children’s bicycles on behalf of the entire 2024 High Roller community, ensuring that their legacy reaches far beyond the ride.
These bikes provide an opportunity for local children in Central Ohio to more easily navigate their environment, experience the pure joy of cycling, and perhaps plant the seeds for a lifelong love of riding and philanthropy. Through the generosity of last year’s High Rollers, the simple act of giving has opened doors of opportunity and inspiration.
All bicycles were gifted to children at Gladden Community House, a cornerstone organization in Franklinton whose mission is to strengthen the well-being of children, families, seniors, and neighborhoods in Central Ohio.
Gladden House interim CEO Matt Burns expressed how much of an impact the donations will have:
“The generous donation of the bikes to Gladden Community House has served to fill the gap in an incredible way for youth, K-12. Students are able to more easily transport themselves to and from Gladden, the local library, and local markets during the summer and will also serve to help many get to school this fall.”
Pelotonia is excited to continue this heartfelt tradition for the 2025 High Rollers by distributing children’s bicycles at the Pelotonia Kids Linden ride.
As Eric Olsavsky, Pelotonia’s Vice President of Community Engagement & Partnerships, shared: “This shift is about making a lasting difference in honor of our High Rollers, whose unwavering spirit inspires everything we do.”
Matt Burns, Interim CEO of Gladden House
Community Stories
The Adventures of Dennis Jacob and Buddy the Bike
| September 19, 2025
Dennis Jacob’s journey with Pelotonia began not just as a cycling challenge, but as a deeply personal mission. In February 2016, Dennis underwent prostate cancer surgery. As he recovered, he set his sights on Pelotonia as both a goal and a symbol of hope.
“I used my first Pelotonia ride as motivation during my recovery,” Dennis said.
That same year, his boss and friend, Rick Germain, launched their company’s first Pelotonia team, offering teammates the choice between fundraising support or a gift card toward a proper road bike. Dennis, then only equipped with a hefty mountain bike, seized the opportunity for a new road bike, one that would become his steadfast companion, affectionately named “Buddy.”
During the next six years, Dennis and Buddy logged an estimated 14,000 miles and participated in seven Pelotonia Ride Weekends, tackling at least 100 miles each year. The pair shared countless moments: cheers from the crowd, laughter with friends, and even a few tears on the toughest stretches. These rides were filled with reminders of why Pelotonia matters: Survivors, patients, and families affected by cancer.
“That bike healed me, kept me sane. It made it possible for me to ride for those who can’t, and the people who love them,” he said.
Dennis, now a 10-Year Rider and Captain of the Germain Peloton, was gifted the bike of his dreams — a Trek Domane SLR6 — in 2023 by his brother and sister-in-law in memory of their daughter, Stevie Rae, a proud supporter of Dennis’ Pelotonia efforts. With the gifted road bike and a newly purchased gravel bike, space was getting tight, and Dennis faced a dilemma: what to do with Buddy? The answer came when he learned about the Pelotonia Bike Fleet. Although an emotional decision because Dennis had been through so much with Buddy, donating the bike meant it would continue its journey, helping others ride for a cure.
For Dennis, giving Buddy to Pelotonia is more than a donation; it’s a continuation of a legacy of hope, healing, and community. Buddy was welcomed with excitement into a new home for the 2025 ride season!
Research Stories
Dr. Katharine Collier Awarded the 2nd Annual Pelotonia-Funded Mason Fisher Grant
| September 19, 2025
Katharine Collier, MD, assistant professor in the Division of Medical Oncology at The Ohio State University and member of the Translational Therapeutics Program at The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute (OSUCCC – James), is the second recipient of the annual Mason Fisher Grant, funded entirely by Pelotonia dollars.
“I am grateful for the support of Pelotonia and the Mason Fisher Grant in my mission to improve personalized and effective treatment for patients with bladder cancer,” Dr. Collier said.
Dr. Collier, who works with bladder and urinary tract cancers, will use the grant to study how patients feel about and are affected by a new, easy genetic test that doesn’t require surgery. This test will be given to up to 500 people who have a type of bladder or urinary tract cancer called urothelial carcinoma. The research aims to learn more about the genetics of this cancer, which is one of the most common cancers in men. Right now, genetic testing isn’t widely recommended for this cancer because we don’t have enough information about the harmful gene changes and how they affect patients.
Her study will explore how simple genetic testing affects patients and families, regardless of cancer stage, age, or family history, and will specifically evaluate associations between genetic mutations and treatment responses. She hopes this project will build a larger cohort to link genetic variants to outcomes and inspire clinical trials for patients with Lynch syndrome or DNA repair mutations, potentially using genetic testing to guide treatment.
Additionally, the project will assess patient and family views on the risks, benefits and psychosocial effects of genetic testing.
This grant extends Dr. Collier’s translational research focused on predictive biomarkers and resistance mechanisms to develop personalized therapies for urothelial carcinoma.
A seven-year Pelotonia Rider, Dr. Collier took part in the 30-mile Sunday route during Ride Weekend 2025 with Team Buckeye – Full Steam Ahead. This combination of grant support and her Pelotonia involvement reflects both her scientific promise and dedication to the cancer research community.
Honoring a Legacy
About the Mason Fisher Grant
The Mason Fisher Grant Program provides early-career faculty members or learners (students, residents, fellows) in Ohio State’s College of Medicine or the OSUCCC – James with up to $50,000 to advance their research of genetic mutations that can lead to cancer.
The grant program honors Mason Fisher, an Ohio State medical student who passed away after a medical event that occurred while he was riding in Ride Weekend 2022. Mason, a three-year Pelotonia Rider who wanted to be a cancer surgeon-scientist, was a passionate advocate for research.
The inaugural Mason Fisher Grant was awarded to Francesca Cottini, MD. She is using the grant funds to enhance research focused on multiple myeloma, a cancer of certain blood cells, and find out why people with this disease are more likely to get other types of blood cancers too.
Research Stories
Study: Genetic Mutations Link Could Lead to New AML Treatment Strategy
| September 19, 2025
Researchers at The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute (OSUCCC – James) and Memorial Sloan Kettering Cancer Center (MSK) have found a connection between two genetic mutations in a subtype of acute myeloid leukemia (AML) — a finding that could lead to new ways to treat this aggressive blood cancer.
Published in the Journal of Clinical Investigation, the study — which involved mouse models of human AML as well as human AML patients — focused on mutations (abnormal changes) in two genes, TP53 and TET2, that cooperate to transform blood cells and play a key role in AML development.
By examining groups of AML patients from the OSUCCC – James and MSK, the scientists saw that 10% of AML patients who have TP53 changes also have TET2 changes — an AML subtype that has very poor clinical outcomes.
The researchers also found that both mice and humans with this subtype displayed high amounts of a molecule called CD155 on their cancer cells, and that using antibodies to block the CD155 molecule helped the immune system destroy the TP53/TET2 cells. This improved patient survival and pointed toward a possible new treatment strategy for patients with this AML subtype.
Authors of the study include Pelotonia-funded researchers Rosa Lapalombella, PhD, co-leader of the Leukemia and Hematologic Malignancies (LHM) Program at the OSUCCC – James; Bradley Blaser, MD, PhD, a member of the LHM Program; and Omar Abdel-Wahab, MD, chair of the Molecular Pharmacology Program at MSK. The study’s first author was Pu Zhang, PhD, a former PhD student and Pelotonia Scholar in Hematology at Ohio State who is now a postdoctoral fellow at MSK.
Read the full story on the OSUCCC – James news page here.
Community Stories
Adam Troy Inspires Linden Community Through Pelotonia, Youth Event, and Service
| June 20, 2025
As a proud Linden resident, Adam Troy is committed to uplifting his community. Adam serves as the Executive Director of the Community of Caring Development Foundation, a nonprofit that invests in the Linden area of Columbus by providing affordable housing, meals, community grants, and academic scholarships.
Adam has used his influence to strengthen the Pelotonia community as well. In addition to being a three-time Rider and Peloton Captain of Team LINDEN and advocate for the Wheels of Color Peloton, Adam is also a cancer Survivor, making Pelotonia’s mission of ending cancer deeply personal. He urges his Linden community to join him in raising funds for innovative cancer research at the OSUCCC – James.
“Now more than ever the need for cancer research funding is vital,” Adam said, referencing an American Cancer Society journal on cancer statistics. “Black and African Americans have the highest mortality rate of any racial and ethnic group for all cancers combined and for most major cancers.”
“It’s up to us as a community to continue to fund ground-breaking research in order to not slow progress toward our One Goal.”
In just three years, Team LINDEN has raised an impressive total of nearly $50,000 for Pelotonia.
Beyond his involvement with the Team LINDEN peloton, Adam also played a vital role in launching Pelotonia Kids Linden in 2024. The neighborhood youth event aimed to promote children’s health and safety through cycling. It also encourages kids to focus on fitness while also fostering community as they came together to raise funds for innovative pediatric cancer research at Nationwide Children’s Hospital and build a brighter future for Columbus youth. Adam brought together additional partners – including philanthropist Renee and Dwight Smith, founders of the Thanks Be to God Foundation, Designer Shoe Warehouse (DSW), New Salem Baptist Church, We Are Linden, the City of Columbus Department of Neighborhoods and Public Safety, Saint Stephen’s Community House, and Columbus City Councilmember Emmanuel Remy – to make the Pelotonia Kids Linden event more impactful. Held in collaboration with the City of Columbus’ Public Safety Week, the inaugural event also featured food trucks, resource tables, and a children’s bike giveaway.
“Events like this give us hope for a brighter tomorrow, laying the groundwork not only for philanthropy in our youth, but also to inspire them to be future community organizers. It’s teaching them the value of service above self,” Adam said.
The next Pelotonia Kids Linden ride is Saturday, August 30, 2025, at Maloney Park in Linden. Scheduled in concert with We Are Linden’s 10th Annual Back to School Block Party and planned in collaboration with last year’s partners, this year’s event will include many of the same fun activities, giveaways, and more. Riders and volunteers are welcomed.
Research Stories
Pelotonia Scholar Excels in Med School, Research, and Ironman
| June 20, 2025
“Anything is possible.” That mantra drives Matthew Marquardt, a third-year medical student at The Ohio State University College of Medicine, dedicated cancer researcher and Pelotonia Scholar, four-time Pelotonia Rider, and professional Ironman triathlete.
Matthew serves as peloton team captain of the BSR–Spin Doctors under the Team Buckeye super peloton and will ride the 100-mile route during Ride Weekend 2025. As a four-year Rider and High Roller, he has made a significant commitment to innovative cancer research at the OSUCCC – James, raising nearly $20,000 during his years of Pelotonia participation.
“I ride in Pelotonia because I want to be a part of creating a cancer-free world. This mission is deeply personal to me,” says Matthew, who honors loved ones affected by cancer by writing their initials on his bike — a symbolic reminder of why he rides.
A 2021 graduate of Princeton University with a degree in chemistry (magna cum laude) and a minor in entrepreneurship, Matthew hopes to become a head and neck cancer surgeon. At the OSUCCC – James, he is involved in three projects that combine medical science, innovation and human performance. His first project, mentored by Carmen Quatman, MD, PhD, in the Department of Orthopaedics, explores the surgeon-athlete connection, examining how principles from sports science can improve surgical performance. His second project, in collaboration with Kyle VanKoevering, MD, in the Department of Otolaryngology and the Medical Modeling, Materials and Manufacturing (M4) Lab, uses 3D printing to enhance surgical outcomes for head and neck cancer patients.
“Matthew blends the science and art of medicine with engineering and technology — the same mindset he applies to training and racing,” Dr. VanKoevering says.
His third project, with David E. Cohn, MD, a gynecologic oncologist who serves as chief operating officer and chief medical officer at the James Cancer Hospital and Solove Research Institute, explores the use of continuous glucose monitoring during chemotherapy to identify metabolic changes.
“He’s one of the most committed and motivated individuals I’ve ever worked with,” Dr. Cohn says.
Matthew’s passion for performance extends far beyond the lab. After discovering triathlon in 2021, he quickly rose through the ranks. He won the overall age-group title at the 2022 IRONMAN World Championship in Kona and turned professional in 2023. That year, he earned three podium finishes and the fastest swim split at the IRONMAN World Championship in Nice. In 2024, he continued to excel with three more podiums and a bike course record at IRONMAN Lake Placid — securing a fourth place finish in the IRONMAN Pro Series. In April 2025, he clocked a sub eight-hour performance at IRONMAN Texas, solidifying his top-30 position in the global PTO World Rankings.
“Triathlon is too hard of a sport to do only by yourself — and so is battling cancer,” he says. “There is incredible power in tackling challenges with others and having a purpose beyond oneself that can positively impact lives.”
As he trains, researches and races, Matthew’s path remains clear: pursue purpose, push limits and help end cancer — one mile, one study and one ride at a time.
Pelotonia Scholar and Med Student at Ohio State
Research Stories
Ohio State Recruits Globally Renowned Researcher in Immunology
| June 20, 2025
In connection to funds raised by the Pelotonia community, Glen Barber, PhD, FRS, a globally distinguished immunologist, was recruited to join the OSUCCC – James’ Pelotonia Institute for Immuno-Oncology (PIIO) as director of the Center for Innate Immunity and Inflammation. His groundbreaking work focuses on the body’s innate immune system, which is considered to be the first line of defense against diseases.
A pivotal achievement of Dr. Barber’s team is the discovery of a signaling pathway controlled by a molecule called STING (Stimulator of Interferon Genes) that is activated by microbes such as viruses, bacteria and parasites. This finding has sparked efforts to design drugs that strengthen the body’s immune system by boosting the STING pathway, which is important for generating antitumor immunity.
“Our goal is to design drugs that stimulate innate immunity and test them in new clinical trials,” Dr. Barber explains.
Dr. Barber’s research also explores the development of vaccines that target viruses linked to cancers. Supported by the National Cancer Institute, these efforts strive to prevent virus-induced cancers through innovative immunological strategies.
Beyond the lab, Dr. Barber is inspired by the community’s commitment to cancer research, exemplified by Pelotonia. He arrived at Ohio State just a day before Ride Weekend 2024, but he’d had his bicycle shipped from Florida to Columbus and joined the Pelotonia community on the 20-mile route the next day.
He shares the OSUCCC – James’ vision of creating a cancer-free world.
“I think it’s possible because there’s so much more to learn, and that means so much opportunity to design ways to combat malignancy,” he explains. “We’re still scratching the surface to a certain extent, but the more we learn through the investment of donors, grants and the cancer center itself, the more team science we can generate and the more trials we can offer. Never say never.”
With a legacy of discovery and a vision for a cancer-free future, Dr. Barber continues to push the boundaries of immunology to develop transformative treatments.
Dr. Glen Barber, PhD, FRS